Obeticholic Acid Powder

What is Obeticholic Acid Powder

Obeticholic Acid Powder is a semi-synthetic bile acid analogue and acts as a farnesoid-X receptor (FXR) agonist. It is used for the treatment of primary biliary cholangitis. It is also under investigation for the treatment of other liver diseases,primary biliary cirrhosis, bile acid diarrhea and related disorders. Study has shown that it also has potential for treating nonalcoholicsteatohepatitis (NASH), and portal hypertension. Obeticholic acid takes effect through acting s the agonist of the farnesoid X receptor (FXR), which is the regulator of bile and cholesterol metabolism in the liver.

Mechanism of action of obeticholic acid powder

Obetocholic acid powder belongs to a class of drugs called Farnesoid X receptor agonists. It regulates bile acid metabolism and bile salt synthesis by binding to farnesoid bile acid receptors in hepatocytes, thereby alleviating biliary inflammation and cholestasis. In addition, obeticholic acid can also regulate liver inflammation and fibrosis processes, helping to improve liver functio

What are the effects of obeticholic acid powder?

1. Stimulate bile secretion

Obetocholic acid powder can stimulate the liver to secrete bile and promote the excretion of bile, thereby alleviating cholestasis;

2. Relieve symptoms of cholestasis

Obetocholic acid powder can relieve nausea, vomiting, abdominal distension and other discomfort symptoms caused by cholestasis;

3. Improve liver function

Obetocholic acid powder can improve liver function, promote liver cell regeneration, and have a certain therapeutic effect on liver damage;

4. Lower serum cholesterol

Obetocholic acid powder can lower serum cholesterol levels, reduce the accumulation of cholesterol in the liver, and have a certain therapeutic effect on hyperlipidemia;

5. Prevent cholelithiasis

Obetocholic acid powder can promote the excretion of bile and reduce the concentration of cholesterol in bile, thereby preventing the occurrence of cholelithiasis.

Indications of Obeticholic Acid Powder

Obeticholic acid is primarily used to treat adults with primary biliary cholangitis. Primary biliary cholangitis is a chronic liver disease that causes the bile ducts in the liver to gradually become damaged and destroyed, eventually leading to liver damage and other related complications. Obeticholic acid plays a key role in the treatment of this disease, helping to reduce inflammation, improve liver function, and control disease progression, thereby improving patients' quality of life.

Dosage and Administration of Obeticholic Acid

Obetocholic acid is generally used in the form of oral medication. The recommended initial dose is usually 10 milligrams (mg) per day. When using this drug, patients should strictly follow the doctor's instructions and prescriptions, and have regular follow-up and blood tests to ensure the safety and effectiveness of treatment. If the dose needs to be adjusted, it should be done according to the doctor's advice.

Precautions for using obeticholic acid powder

Although obeticholic acid can effectively treat PBC, the following precautions should be taken when using this drug:

1 Dosage: The dose of obeticholic acid needs to be adjusted according to the patient's specific situation. Before starting use, the doctor will evaluate the patient's liver function and bile acid levels to determine the most appropriate dose.

2 Liver function monitoring: During treatment with obeticholic acid, patients need to undergo regular liver function monitoring, including testing liver enzymes and bile acid levels. This helps to detect and treat liver problems related to drug treatment early.

3 Pregnancy and lactation: The safety of obeticholic acid during pregnancy and lactation has not been fully studied, so the drug should be used with caution during these periods and under the guidance of a doctor.

4 Drug interactions: Obeticholic acid may interact with other drugs, affecting its efficacy or increasing the risk of adverse reactions. Before using obeticholic acid, you should consult your doctor or pharmacist in detail about other drugs you are using.

Packaging and Transportation:

General packaging：

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 5kg/carton(1kg net weight, 1.1kg gross weight, packed in five aluminum foil bag)

3) 25kg/drum (25kg net weight, 28kg gross weight;)

Quality Standards and Certifications

Our product adheres to the highest quality standards and holds numerous certifications, ensuring global recognition and trust:

FDA-Salis HALAL ISO CCRE5 USDA Organic EU Organic

Contact US

If you want to buy obeticholic acid powder please contact us for more details iceyqiang@aliyun.com

FAQ

Q1: Can i get some samples?

A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2: How to start orders or make payments?

A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Escrow(Alibaba).

Q3: How to confirm the Product Quality before placing orders?

A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the

samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q4:What's your MOQ?

A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Q5: How about delivery lead time?

A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)